Wednesday, 8th November
Australia and New Zealand Society for Extracellular Vesicles Conference 2023
Days
Tuesday, 7th November
Wednesday, 8th November
Thursday, 9th November
Friday, 10th November
Search
Speakers
Morning Tea & Coffee
11:00AM - 11:30AM
Wednesday, 8th November
Pre-Function Area
Opening
11:30AM - 11:35AM
Wednesday, 8th November
Shiraz Room
Welcome to Country
11:35AM - 11:40AM
Wednesday, 8th November
Shiraz Room
International Invited Speaker Presentation
11:40AM - 12:15PM
Wednesday, 8th November
Shiraz Room
Chair: Andrew Rowland
Malaria's Communicators: Extracellular Vesicles in Survival Strategies
-
Neta Regev-rudzki
National Invited Speaker Presentation
12:15PM - 12:40PM
Wednesday, 8th November
Shiraz Room
Chair: Andrew Rowland
Optimisation and Applications of Small Extracellular Vesicles (sEVs) in Regenerative Medicine
-
Haiyan Li
Sponsor Presentations
12:40PM - 1:00PM
Wednesday, 8th November
Shiraz Room
Izon & DKSH
Particle Metrix
Lunch
1:00PM - 1:45PM
Wednesday, 8th November
The Cellar Kitchen Restaurant
Poster Session
1:45PM - 3:00PM
Wednesday, 8th November
Cabernet Room
Brining Extracellular Vesicles into Focus: Use of Extracellular Vesicles in the Treatment of Retinal Degenerations
-
Riccardo Natoli
Exploring the role of extracellular vesicles in endometriosis
-
Hadassah Patchigalla
Cell-Free Nanotherapy Platform Technologies as Revolutionary Regenerative Immunotherapy
-
Gibeom Kim
Investigating the impact of bacterial outer membrane vesicles on alveolar macrophage responses
-
Isabella Stuart
Gene expression profile of exosomes reflects their parent cells in a cardiac disease model
-
Jane Synnergren
Investigating cervicovaginal fluid extracellular vesicles for diagnostic endometriosis biomarkers: a pilot study
-
Emily S. J. Paterson
How do extracellular vesicles from human cells influence the transcriptome of
Escherichia coli
?
-
Simon Swift
Microglial activation induces nitric oxide signalling and alters protein nitrosylation patterns in extracellular vesicles
-
Natasha Vassileff
Role of ubiquitin K29 chains in the biogenesis of extracellular vesicles
-
Yoon Lim
Isolation and characterisation of extracellular vesicles from cryoprecipitate and FFP
-
Ji Hui Hwang
Isolation, characterization, and immunomodulatory effects of extracellular vesicles from
Arthrospira
(
Spirulina
)
platensis
-
Mohammad Farouq Sharifpour
A Pilot Study to Ascertain the Feasibility of Using Mesenchymal Stem Cells-derived Growth Factors and Cytokines to Ameliorate Progression of Diabetic Foot Ulcers
-
Kuldip S Sidhu
Extracellular vesicles from packed red blood cell supernatants: incompletely depleted by filtration
-
Rebecca Wellburn
A novel pathogen sensing platform for detection of
Escherichia Coli
in Water
-
Shiana Malhotra
Age-related changes in coagulation and extracellular particles: a pilot study
-
Caroline Reddel
Milk Talks: the role of breastmilk extracellular vesicles in preventing intergenerational obesity
-
Farha Ramzan
Tug-of-war between senescence and Wnt signaling: implications in the biogenesis and secretion of small extracellular vesicles
-
Pamali Fonseka
Extracellular vesicle PD-L1 as an indicator of immunotherapy response in melanoma patients: Are we ready for clinical application?
-
Cherie Blenkiron
The role of mitochondrial quality control in response to
Neisseria gonorrhoeae
outer membrane vesicles
-
Chantelle Blyth
Enhancing Exosome Secretion in MSCs by Modulating Substrate Stiffness and Dimensionality
-
Riddhesh Doshi
A multivalent extracellular vesicle therapy for treating SARS-CoV-2 infection and long COVID
-
Paniz Shirmast
Unconventional protein trafficking for extracellular vesicle packaging
-
Monika Petrovska
EXOSOME PROTEOMICS AND POTENCY TESTING – PAVING THE WAY TO THERAPY Exosomes are emerging as superstars amidst the myriad of other soluble and trophic factors that mesenchymal stem cells (MSCs) secrete; and rightfully so, as these mediators of intercellular communication carry the inherent immunomodulatory capacity and therapeutic vigour of MSCs. Previously, the identity, purity and safety of ENDEXOME EXO
TM
, nanovesicles isolated from our proprietary immortalised MSC lines, have been reported using various techniques including Nano Flow Cytometry. We showed >97% of an intact EV population with a size of 50-200 nm, transmembrane identity markers such as CD63 and CD81; identity markers CD73 and CD105 establishing mesenchymal origin. Given the functional heterogeneity of Extracellular vesicles, it becomes imperative to evaluate their potency prior to clinical administration. In this study, we aim to validate potency of our ENDEXOME EXO
TM
using elaborate adaptations of established functional assays and MSC-specific assays. Next, we take a comprehensive approach to characterise and analyse the surfaceome (total number surface membrane proteins on exosomes) of all our ENDEXOME EXO
TM
with an aim to comprehensively characterise their distinct components including but not limited to integral membrane proteins (IMPs), peripherally associated membrane proteins (PMPs), RNA-binding Proteins (RBPs), RNA nucleoproteins (RNPs) in addition to surface-localised microRNAs (miRNAs) bound to the outer exosome surface, using mass spectrometry based protein identification and comprehensive proteomics profiling. This instils confidence towards the potential and practicality of using our novel exosomal entities in therapeutic modalities for disease treatment.
-
Devashree Vakil
High-throughput isolation of extracellular vesicles and associated miRNAs
-
Carlos Palma
A novel engineered protein bead-based matrix for enrichment of tumor derived extracellular vesicles
-
Sara Nikseresht
Electrochemical Platforms for Detection of Extracellular Vesicles and Cancer Biomarkers
-
Zarinah Amin
Targeted activation of AMPK1 alpha subunit kinase activity by RNA regulation of PRKAA1 splice variant expression
-
Riccardo Cecchin
Caffeine alters extracellular vesicle production and composition in male population and prostate cancer cells.
-
Jess Heatlie
Exploiting helminth extracellular vesicle corona proteins for targeted hookworm vaccine development
-
Tamara S Thomas
Development of a chemical antibody (aptamer) to human CD9
-
Wei Duan
Establishing a robust exosome manufacturing process for translational studies
-
Smriti Murali Krishna
EV customisation strategies and their therapeutic potential
-
Ella L Johnston
From Laboratory to Manufacturing; Methods and Challenges in Exosome Purification
-
Mitch Shambrook
Proteomic profiling of paired human liver homogenate and tissue derived extracellular vesicles
-
Zivile Useckaite
A PI3K signalling regulator that promotes the formation and release of pro-migratory EVs in breast cancer.
-
Sabryn A Hamila
Characterising platelet-rich and platelet-poor plasma EV sampling bias for proteomic biomarker studies
-
Samantha J Emery-Corbin
Current Advances in Nanoparticle Tracking Analysis - Colocalization of Biomarkers with the New Particle MetrixZetaView x30 Family
-
Sven Kreutel
Agonist specific sorting of proteins into platelet extracellular vesicles
-
Mitchell J Moon
EV Biology, Biogenesis & Biomarkers Session
3:00PM - 4:00PM
Wednesday, 8th November
Shiraz Room
Chairs: Lesley Cheng & Emma Symonds
The protein composition of the tumour-derived extracellular vesicles varies by endometrial cancer histology and an obesogenic environment
-
Anastasiia Artuyants
Helicobacter pylori
cytotoxin, VacA, hijacks dendritic cell extracellular vesicles to dysregulate immune cell functions
-
Ruby Gorman-Batt
Eukaryotic and microbiota-derived extracellular vesicles in Parkinson’s disease.
-
Laura Vella
Phospholipid scrambling: a novel regulator of extracellular vesicle cargo packaging and function
-
Sarah E Stewart
Afternoon Tea & Exhibition
4:00PM - 4:30PM
Wednesday, 8th November
Pre-Function Area
National Invited Speaker Presentation
4:30PM - 4:55PM
Wednesday, 8th November
Shiraz Room
Chairs: Thomas Naderer & Jancy Johnson
Outer membrane vesicle vaccines for gonorrhoea
-
Kate L Seib
Wine Tasting Welcome Function
6:00PM - 8:00PM
Wednesday, 8th November
Novotel Lawn Area
← Tuesday
Thursday →